Selected-GenAtlas references | SOURCE | GeneCards | NCBI Gene | Swiss-Prot | Ensembl |
HGNC | UniGene | Nucleotide | OMIM | UCSC |
Home Page |
FLASH GENE |
Symbol | CYP46A1 | contributors: shn - updated : 14-06-2010 |
HGNC name | cytochrome P450, family 46, subfamily A, polypeptide 1 |
HGNC id | 2641 |
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ASSOCIATED DISORDERS |
corresponding disease(s) |
Susceptibility |
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Variant & Polymorphism SNP | rs754203 polymorphism increasing the risk of Alzheimer's disease in a Chinese population ![]() |
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Candidate gene | candidate for retinal pathologies like age-related macular degeneration or glaucomas ![]() | |
Marker
Therapy target
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ANIMAL & CELL MODELS |
Cyp46a1-/- mice display unchanged hepatic cholesterol and bile acid metabolism parameters while the synthesis of new cholesterol is reduced by 40% in the brain ![]() |