Symbol
| RCE1
| contributors: mct/npt/pgu - updated : 08-07-2009
|
HGNC name
| RCE1 homolog, prenyl protein protease (S. cerevisiae)
|
HGNC id
| 13721
|
Variant & Polymorphism
|
| |
Candidate gene
Marker
Therapy target
|
System | Type | Disorder | Pubmed |
cancer | | | |
peptidomimetic inhibitors of RCE1 may be useful in treatment of cancer | immunology | inflammatory | | |
peptidomimetic inhibitors of RCE1 may be useful in treatment of inflammatory disease |
| | | |
| hearts from heart-specific Rce1 knockout mice manifested reduced levels of both the Rce1 mRNA and CAAX endoprotease activity, and the hearts manifested an accumulation of CAAX protein substrates; heart-specific Rce1 knockout mice had a dilated cardiomyopathy |