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FLASH GENE

Symbol

RNF7

contributors: mct/npt - updated : 10-06-2020

HGNC name	ring finger protein 7
HGNC id	10070

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function tumoral     --over   progressively from early-to-late stage of human prostate cancer with the highest expression seen in metastatic lesion

Susceptibility

Variant & Polymorphism

Candidate gene
Marker	may be a candidate gene for good prognosis, in rectal cancer, independent of therapeutic response of different individuals
Therapy target
	System Type Disorder Pubmed cancer reproductive prostate targeting RNF7 E3 ligase may, therefore, have therapeutic value for the treatment of prostate cancer associated with PTEN loss (pM

ANIMAL & CELL MODELS