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FLASH GENE
Symbol RNF7 contributors: mct/npt - updated : 10-06-2020
HGNC name ring finger protein 7
HGNC id 10070
ASSOCIATED DISORDERS
corresponding disease(s)
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
tumoral     --over  
progressively from early-to-late stage of human prostate cancer with the highest expression seen in metastatic lesion
Susceptibility
Variant & Polymorphism
Candidate gene
Marker
  • may be a candidate gene for good prognosis, in rectal cancer, independent of therapeutic response of different individuals
  • Therapy target
    SystemTypeDisorderPubmed
    cancerreproductiveprostate
    targeting RNF7 E3 ligase may, therefore, have therapeutic value for the treatment of prostate cancer associated with PTEN loss (pM
    ANIMAL & CELL MODELS