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FLASH GENE
Symbol CHI3L2 contributors: mct - updated : 12-06-2015
HGNC name chitinase 3-like 2
HGNC id 1933
ASSOCIATED DISORDERS
corresponding disease(s)
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
constitutional     --low  
CSF CHI3L2 levels were lower in progressive multiple sclerosis (MS) than in relapsing-remitting MS (RRMS) patients
constitutional     --over  
in osteoarthritic articular chondrocytes suggesting the involvement of CHI3L2 in the progression of osteoarthritis (OA)
Susceptibility
Variant & Polymorphism
Candidate gene
Marker
  • potential marker for the activation of chondrocytes and the progression of osteoarthritis
  • Therapy target
    ANIMAL & CELL MODELS