| Other morbid association(s)
|
| Type | Gene Modification | Chromosome rearrangement | Protein expression | Protein Function
|
|---|
| tumoral
|
|
| --low
|
| |
at the early stage of colorectal and stomach carcinogenesis | | tumoral
| somatic mutation
|
|
|
| |
in colon and lung cancer | | constitutional
|
|
|
| gain of function
| |
at specific stages of spermatogenesis, suggesting that they play an important role in the epigenetic reprogramming during spermatogenesis (Wawrzik 2009) | | constitutional
|
|
| --low
|
|
decreased expression of MBD2 and MBD4 might involve in the pathogenesis of primary immune thrombocytopenia  | | constitutional
|
|
| --over
|
| |
of the MBD2 and MBD4 genes in CD4+ T cells from systemic lupus erythematosus patients | |
