Other morbid association(s)
|
Type | Gene Modification | Chromosome rearrangement | Protein expression | Protein Function
|
---|
tumoral
|  
|  
| --low
|  
|
at the early stage of colorectal and stomach carcinogenesis | tumoral
| somatic mutation
|  
|  
|  
|
in colon and lung cancer | constitutional
|  
|  
|  
| gain of function
|
at specific stages of spermatogenesis, suggesting that they play an important role in the epigenetic reprogramming during spermatogenesis (Wawrzik 2009) | constitutional
|  
|  
| --low
|  
|
decreased expression of MBD2 and MBD4 might involve in the pathogenesis of primary immune thrombocytopenia  | constitutional
|  
|  
| --over
|  
|
of the MBD2 and MBD4 genes in CD4+ T cells from systemic lupus erythematosus patients  | |