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FLASH GENE

Symbol

KAT2B

contributors: shn/npt/pgu - updated : 04-03-2016

HGNC name	K(lysine) acetyltransferase 2B
HGNC id	8638

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Susceptibility

to survival advantage in elderly patients

Variant & Polymorphism SNP	the -2481C allele in the promoter is associated with a significant survival advantage in elderly patients

Candidate gene
Marker
Therapy target
	System Type Disorder Pubmed cancer     new rationale for therapeutic targeting of KAT2B activity in tumors harboring oncogenic versions of TP53

ANIMAL & CELL MODELS