Symbol
| ELF5
| contributors: mct/ - updated : 28-06-2022
|
HGNC name
| E74-like factor 5 (ets domain transcription factor)
|
HGNC id
| 3320
|
Other morbid association(s)
|
Type | Gene Modification | Chromosome rearrangement | Protein expression | Protein Function
|
---|
constitutional
|  
|  
| --low
|  
|
hypermethylated and largely repressed in embryonic stem cells and derived trophoblast cell lines (Hemberger 2010) | tumoral
|  
|  
| --low
|  
|
in ovarian cancer cell lines | |
Variant & Polymorphism
|
| |
Candidate gene
Marker
Therapy target
|
System | Type | Disorder | Pubmed |
cancer | reproductive | breast | |
ELF5 inhibit breast cancer from a new perspective and provides further theoretical support for the treatment and prevention of breast cancer | cancer | reproductive | ovary | |
could provide a new approach to gene treatment of ovarian carcinoma |
| | | |