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FLASH GENE
Symbol ELF5 contributors: mct/ - updated : 28-06-2022
HGNC name E74-like factor 5 (ets domain transcription factor)
HGNC id 3320
ASSOCIATED DISORDERS
corresponding disease(s)
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
constitutional     --low  
hypermethylated and largely repressed in embryonic stem cells and derived trophoblast cell lines (Hemberger 2010)
tumoral     --low  
in ovarian cancer cell lines
Susceptibility
Variant & Polymorphism
Candidate gene
Marker
Therapy target
SystemTypeDisorderPubmed
cancerreproductivebreast
ELF5 inhibit breast cancer from a new perspective and provides further theoretical support for the treatment and prevention of breast cancer
cancerreproductiveovary
could provide a new approach to gene treatment of ovarian carcinoma
ANIMAL & CELL MODELS