Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol TNFRSF17 contributors: mct - updated : 19-01-2016
HGNC name tumor necrosis factor receptor superfamily, member 17
HGNC id 11913
ASSOCIATED DISORDERS
corresponding disease(s)
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
constitutional     --over  
in primary Sjogren syndrome
tumoral   translocation    
T cell malignant lymphoma with t(4;16)(q26;p13)
constitutional     --over  
with TNF, TNFSF13B, TNFSF13 in Behcet disease
constitutional     --over  
in inflammatory skin lesions of psoriasis
tumoral     --over  
in skin squamous cell carcinomas
constitutional     --over  
in systemic lupus erythematosus (SLE)
Susceptibility to UC (ulcerative colitis) and IBD (inflammatory bowel disease)
Variant & Polymorphism other
  • haplotypes of the TNFRSF17 polymorphisms might be associated with UC and IBD susceptibility
  • Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS
    BCMA-/- knockout mice,developing systemic lupus erythematosis