Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol TNFRSF10A contributors: mct - updated : 07-01-2015
HGNC name tumor necrosis factor receptor superfamily, member 10a
HGNC id 11904
ASSOCIATED DISORDERS
corresponding disease(s)
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
tumoral   deletion    
in nasopharyngeal cancer
Susceptibility to cancer
Variant & Polymorphism SNP
  • A683C with tumor specific allele distribution
  • A1322G G allele and A683C C allele are associated with increased risk for cancer
  • Candidate gene
    Marker
    Therapy target
  • cytotoxic agents capable of up-regulating the expression of TNFRSF10A and TNFRSF10B can sensitize cancer cells to TNFSF10 induced apoptosis
  • ANIMAL & CELL MODELS