Symbol
| ADAMTS4
| contributors: mct - updated : 18-09-2015
|
HGNC name
| ADAM metallopeptidase with thrombospondin type 1 motif, 4
|
HGNC id
| 220
|
Other morbid association(s)
|
Type | Gene Modification | Chromosome rearrangement | Protein expression | Protein Function
|
---|
constitutional
|  
|  
| --low
|  
|
required to inhibit aggrecan degradation in human OA cartilage | tumoral
|  
|  
| --over
|  
|
in Ewing sarcoma | constitutional
|  
|  
| --over
|  
|
in acute coronary syndrome | constitutional
|  
|  
| --low
|  
|
in the maternal and cord blood were lower in the preeclampsia group than in the control group | |
Variant & Polymorphism
|
| |
Candidate gene
Marker
| is potentially a novel tumor marker for Ewing sarcoma | |
its expression may be a valuable marker for predicting the severity of acute coronary syndrome | |
| Therapy target
| | |