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FLASH GENE
Symbol DAAM1 contributors: mct/pgu - updated : 31-08-2016
HGNC name dishevelled associated activator of morphogenesis 1
HGNC id 18142
ASSOCIATED DISORDERS
corresponding disease(s)
Susceptibility
Variant & Polymorphism
Candidate gene
Marker
Therapy target
ANIMAL & CELL MODELS
  • Daam1-deficient mice exhibit embryonic and neonatal lethality and suffer multiple cardiac defects, including ventricular noncompaction, double outlet right ventricles and ventricular septal defects
  • homozygous Daam1 conditional knockout (CKO) mice were viable but had misshapen hearts and poor cardiac function