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FLASH GENE
Symbol DIDO1 contributors: mct - updated : 06-12-2014
HGNC name death inducer-obliterator 1
HGNC id 2680
ASSOCIATED DISORDERS
corresponding disease(s)
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
tumoral     --other  
altered expression implicated in the induction of hematological myeloid neoplasms
tumoral     --over  
in melanoma cell lines
Susceptibility
Variant & Polymorphism
Candidate gene
Marker
Therapy target
ANIMAL & CELL MODELS
  • targeted disruption causes a transplantable myelodysplastic/myeloproliferative disease in mice (Trachana (07)
  • specific ablation of Dido3 function in mice causes lethal developmental defects at the onset of gastrulation