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FLASH GENE
Symbol F2 contributors: SGE/npt - updated : 28-11-2007
HGNC name coagulation factor II (thrombin)
HGNC id 3535
ASSOCIATED DISORDERS
corresponding disease(s) F2
Susceptibility to ischemic heart disease (IHD)
Variant & Polymorphism other G20210A heterozygosity alone and in combination with Factor V Leiden R506Q heterozygosity predicts 1.5 and 6.0 fold risk of IHD compared to non-carriers (Weischer 2009)
Candidate gene
Marker
Therapy target
ANIMAL & CELL MODELS