Symbol
| LSAMP
| contributors: mct/npt - updated : 09-06-2020
|
HGNC name
| limbic system-associated membrane protein
|
HGNC id
| 6705
|
Other morbid association(s)
|
Type | Gene Modification | Chromosome rearrangement | Protein expression | Protein Function
|
---|
tumoral
|  
| LOH
|  
|  
|
in osteosarcoma (Yen 2009) | tumoral
|  
| deletion
|  
|  
|
in osteosarcomas (Kresse 2009) | tumoral
|  
|  
| --over
|  
|
of the LSAMP and TUSC7 genes in acute myeloid leukemia | |
Susceptibility
|
to late-onset coronary artery disease (CAD) to ulcerative colitis (UC) to schizophrenia |
Variant & Polymorphism
SNP
| increasing the risk of late-onset coronary artery disease (CAD)(Wang 2008) |
|
SNPs at ZNF649 and LSAMP, with associations of genome-wide significance for UC |
|
significant allelic and haplotypic associations between LSAMP gene and schizophrenia |
|
|
Candidate gene
Marker
Therapy target
| | | |