Symbol
| RAB13
| contributors: mct - updated : 14-09-2022
|
HGNC name
| RAB13, member RAS oncogene family
|
HGNC id
| 9762
|
Other morbid association(s)
|
Type | Gene Modification | Chromosome rearrangement | Protein expression | Protein Function
|
---|
constitutional
|  
|  
| --other
|  
|
present in apical tight junctions in normal epithelium but were dislocated to the basolateral position in patients with inactive Crohn disease ( | |
Variant & Polymorphism
|
| |
Candidate gene
Marker
Therapy target
|
System | Type | Disorder | Pubmed |
cancer | reproductive | breast | |
Targeting Rab13 perturbs formation of the breast cancer stem cell niche by inhibiting cross-talk between cancer cells and the tumor microenvironment, providing a therapeutic opportunity for niche-targeted breast cancer treatment | cancer | | | |
blocking RAB13 activation by ST5 may provide a novel target to limit the spread of epithelial cancers |
| | | |