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FLASH GENE
Symbol BNIP3L contributors: mct - updated : 04-10-2017
HGNC name BCL2/adenovirus E1B 19kDa interacting protein 3-like
HGNC id 1085
ASSOCIATED DISORDERS
corresponding disease(s)
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
tumoral   LOH    
LOH in carcinomas of the colon, prostate, liver and lung
Susceptibility
Variant & Polymorphism
Candidate gene
Marker
Therapy target
  • may be a novel therapeutic target for intervention because of its pathological roles in regulating cell deth in disease states
  • ANIMAL & CELL MODELS
  • Nix(-/-) mice developed anaemia with reduced mature erythrocytes and compensatory expansion of erythroid precursors
  • retinas from Nix-deficient mice displayed increased mitochondrial mass, reduced expression of glycolytic enzymes and decreased neuronal differentiation