Other morbid association(s)
|
Type | Gene Modification | Chromosome rearrangement | Protein expression | Protein Function
|
---|
constitutional
|  
|  
|  
| loss of function
|
inducing a lysosomal storage disorder showing the accumulation of lysosomal membrane sialoglycoproteins (LAMP1, LAMP2, SCARB2) and the elevation of lysosomal pH in macrophages | tumoral
|  
|  
| --over
|  
|
in gastric and cervical adenocarcinomas, in lung adenocarcinomas and squamous cell carcinomas, and in pancreatic ductal adenocarcinomas (Zaidi 2008) | |