Symbol
| RAC2
| contributors: mct/pgu - updated : 04-11-2016
|
HGNC name
| ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
|
HGNC id
| 9802
|
corresponding disease(s)
|
NIDS
|
Other morbid association(s)
|
Type | Gene Modification | Chromosome rearrangement | Protein expression | Protein Function
|
---|
constitutional
|  
|  
| --low
|  
|
in severe congenital neutropenia | tumoral
|  
|  
| --low
|  
|
exhausts the leukemic stem cells pool, through impairment of oncogene-induced proliferation and survival signals | |
Variant & Polymorphism
|
| |
Candidate gene
Marker
Therapy target
| | | |
| Rac2(-/-) mice are of normal size and have normal tooth eruption, but femoral cortical thickness was significantly greater compared to wild-type mice |