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FLASH GENE
Symbol WNT7B contributors: mct - updated : 04-07-2018
HGNC name wingless-type MMTV integration site family, member 7B
HGNC id 12787
ASSOCIATED DISORDERS
corresponding disease(s)
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
tumoral     --over  
in breast carcinoma and gastric cancer
constitutional       gain of function
abnormal upregulation in the levels of WNT2B and WNT7B in neural tube defects (NTDs)
Susceptibility
Variant & Polymorphism
Candidate gene
Marker
Therapy target
ANIMAL & CELL MODELS
in mouse, Wnt7b-null lungs are markedly hypoplastic, yet display largely normal patterning and cell differentiation