Symbol
| WNT7B
| contributors: mct - updated : 04-07-2018
|
HGNC name
| wingless-type MMTV integration site family, member 7B
|
HGNC id
| 12787
|
Other morbid association(s)
|
Type | Gene Modification | Chromosome rearrangement | Protein expression | Protein Function
|
---|
tumoral
|  
|  
| --over
|  
|
in breast carcinoma and gastric cancer | constitutional
|  
|  
|  
| gain of function
|
abnormal upregulation in the levels of WNT2B and WNT7B in neural tube defects (NTDs) | |
Variant & Polymorphism
|
| |
Candidate gene
Marker
Therapy target
| | | |
| in mouse, Wnt7b-null lungs are markedly hypoplastic, yet display largely normal patterning and cell differentiation |