Symbol
| FZD5
| contributors: mct/npt - updated : 31-03-2017
|
HGNC name
| frizzled homolog 5 (Drosophila)
|
HGNC id
| 4043
|
corresponding disease(s)
|
CLBM1
|
Other morbid association(s)
|
Type | Gene Modification | Chromosome rearrangement | Protein expression | Protein Function
|
---|
tumoral
|  
|  
| --over
|  
|
in chronic myelogenous leukemia | constitutional
|  
|  
| --over
|  
|
during the acquisition of neuronal polarity induces mislocalization of the receptor and a loss of polarized axonal markers | |
Variant & Polymorphism
|
| |
Candidate gene
Marker
Therapy target
| | | |
| Fz5(-/-) mice exhibit mild coloboma and microphthalmia at 50p100 of penetrance | |
mutant protein caused coloboma and microphthalmia in zebrafish |