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FLASH GENE
Symbol CNGB1 contributors: mct - updated : 09-05-2018
HGNC name cyclic nucleotide gated channel beta 1
HGNC id 2151
ASSOCIATED DISORDERS
corresponding disease(s) ARRP16
Susceptibility
Variant & Polymorphism
Candidate gene
Marker
Therapy target
SystemTypeDisorderPubmed
neurosensorialvisualretina
modulation of rod CNGB1 channel activity is a most promising target for the treatment in retinal degenerations with elevated cellular levels of cGMP
ANIMAL & CELL MODELS
  • treated by gene therapy CNGB1-/- mice gained the ability to navigate using information provided by the rod visual system