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FLASH GENE
Symbol SOX12 contributors: mct - updated : 22-12-2015
HGNC name SRY (sex determining region Y)-box 12
HGNC id 11198
ASSOCIATED DISORDERS
corresponding disease(s)
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
tumoral     --over  
induced by FOXQ1 promotes hepatocellular invasion and metastasis by transactivating TWIST1 and FGFBP1 expression
Susceptibility
Variant & Polymorphism
Candidate gene
Marker
  • potential prognostic biomarker in hepatocellular carcinoma
  • Therapy target
    SystemTypeDisorderPubmed
    cancerdigestiveliver
    novel therapeutic target for hepatocellular carcinoma
    ANIMAL & CELL MODELS
  • Sox12-deficient mice developed surprisingly normally, so that they were born alive, showed no gross phenotypic abnormalities, and were fertile in both sexes