Symbol
| SOX12
| contributors: mct - updated : 22-12-2015
|
HGNC name
| SRY (sex determining region Y)-box 12
|
HGNC id
| 11198
|
Other morbid association(s)
|
Type | Gene Modification | Chromosome rearrangement | Protein expression | Protein Function
|
---|
tumoral
|  
|  
| --over
|  
|
induced by FOXQ1 promotes hepatocellular invasion and metastasis by transactivating TWIST1 and FGFBP1 expression | |
Variant & Polymorphism
|
| |
Candidate gene
Marker
| potential prognostic biomarker in hepatocellular carcinoma | Therapy target
|
System | Type | Disorder | Pubmed |
cancer | digestive | liver | |
novel therapeutic target for hepatocellular carcinoma |
| | |
| Sox12-deficient mice developed surprisingly normally, so that they were born alive, showed no gross phenotypic abnormalities, and were fertile in both sexes |