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FLASH GENE
Symbol PDLIM4 contributors: mct - updated : 19-03-2010
HGNC name PDZ and LIM domain 4
HGNC id 16501
ASSOCIATED DISORDERS
corresponding disease(s)
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
tumoral     --low  
by hypermethylation in renal cell carcinoma
tumoral     --low  
by hypermethylation in acute myelogenous leukemia and colon cancer (60 p100 of cases)
Susceptibility to osteoporosis
Variant & Polymorphism
Candidate gene
Marker
Therapy target
SystemTypeDisorderPubmed
cancer  
good candidate tumor suppressor gene silenced by hypermethylation in cancer
ANIMAL & CELL MODELS