Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol GSC2 contributors: mct - updated : 11-03-2011
HGNC name goosecoid homeobox 2
HGNC id 4613
ASSOCIATED DISORDERS
corresponding disease(s)
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
constitutional   deletion    
in Di George syndrome
constitutional        
loss of GSC2 and DGCR14 affects the regulation of hippocampal theta and rapid eye movement sleep, possibly contributing to the psychiatric symptoms frequently seen in patients who have 22q11 syndrome
Susceptibility
Variant & Polymorphism
Candidate gene
Marker
Therapy target
ANIMAL & CELL MODELS
  • Gscl&
  • 8722;/&
    8722; mice have apparently normal anatomy and connections of the interpeduncular nucleus, but they exhibited a reduced total time spent in REM sleep and fewer rapid eye movement sleep (REM) episodes