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FLASH GENE
Symbol TRIO contributors: npt/mct - updated : 19-09-2017
HGNC name triple functional domain (PTPRF interacting)
HGNC id 12303
ASSOCIATED DISORDERS
corresponding disease(s) MRD44
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
tumoral   amplification --over  
in soft tissue sarcomas
Susceptibility
Variant & Polymorphism
Candidate gene
Marker
Therapy target
ANIMAL & CELL MODELS
  • heterozygous or homozygous deletion of Trio in the hippocampus and in the cortex during early embryogenesis results in progressive defects in learning ability, sociability, and motor coordination of these mice