Symbol
| ACACB
| contributors: mct/npt/shn - updated : 07-06-2016
|
HGNC name
| acetyl-CoA carboxylase beta
|
HGNC id
| 85
|
Other morbid association(s)
|
Type | Gene Modification | Chromosome rearrangement | Protein expression | Protein Function
|
---|
constitutional
|  
| deletion
|  
|  
|
Cardiac-specific deletion of ACACB prevents metabolic remodeling during pressure-overload hypertrophy  | |
Susceptibility
|
to obesity and diabetes |
Variant & Polymorphism
|
| |
Candidate gene
Marker
Therapy target
| therapeutic target for obesity and diabetes (Cho 2010) |
| | |
| Acc2-/- mutant mice have a normal life span, a higher fatty acid oxidation rate, and lower amounts of fat  |