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FLASH GENE
Symbol AIM1 contributors: mct - updated : 22-12-2015
HGNC name absent in melanoma 1
HGNC id 356
ASSOCIATED DISORDERS
corresponding disease(s)
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
tumoral     --over  
in prostate cancer tissues
tumoral     --low  
by promoter hypermethylation identified in 65p100 of metastatic melanomas, as compared to 38p100 of primary melanomas
Susceptibility
Variant & Polymorphism
Candidate gene
Marker
Therapy target
SystemTypeDisorderPubmed
cancerreproductiveprostate
induction of apoptosis due to AIM1 and TMED3 inhibition especially in the androgen independent prostate cancer cells
ANIMAL & CELL MODELS