Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol RBM3 contributors: mct - updated : 28-01-2015
HGNC name RNA binding motif protein 3
HGNC id 9900
ASSOCIATED DISORDERS
corresponding disease(s)
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
tumoral     --low  
associated with clinically more aggressive tumours and an independent factor of poor prognosis in patients with urothelial bladder cancer
tumoral     --over  
of RBM3 is an independent predictor of good prognosis in colorectal cancer
constitutional     --over  
decreases muscle cell necrosis as well as apoptosis and therefore RBM3 could potentially serve as an intervention for the loss of muscle cell viability during muscle atrophy and muscle diseases
Susceptibility
Variant & Polymorphism
Candidate gene
Marker
Therapy target
ANIMAL & CELL MODELS
  • Rbm3(-/-) mouse embryonic fibroblasts (MEFs) showed poorer proliferation rates as compared to control MEFs, and have markedly increased number of G2-phase cells, suggesting a hitherto unknown role of RBM3 in the G2-phase control