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FLASH GENE
Symbol POLB contributors: mct/npt - updated : 03-02-2015
HGNC name polymerase (DNA directed), beta
HGNC id 9174
ASSOCIATED DISORDERS
corresponding disease(s)
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
tumoral     --low  
is an underlying cause of systemic lupus erythematosus (SLE)
Susceptibility
  • to gastric, colon, prostate carcinoma
  • Variant & Polymorphism other
  • variant increasing the risk of carcinoma
  • people who carry the rs3136797 germline SNP may be at an increased risk for cancer susceptibility
  • Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS