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FLASH GENE

Symbol

PENK

contributors: mct - updated : 13-11-2007

HGNC name	proenkephalin
HGNC id	8831

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function tumoral     --low   by hypermethylation in pancreatic intraepithelial neoplasia and pancreatic ductal adenocarcinoma

Susceptibility

not contributing to the susceptibility of bipolar affective disorder to opioid dependence

Variant & Polymorphism other	polymorphisms increasing the risk of opioid dependence

Candidate gene	useful indicator of the potential malignancy of epithelial cells of the pancreas
Marker
Therapy target

ANIMAL & CELL MODELS