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FLASH GENE
Symbol PENK contributors: mct - updated : 13-11-2007
HGNC name proenkephalin
HGNC id 8831
ASSOCIATED DISORDERS
corresponding disease(s)
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
tumoral     --low  
by hypermethylation in pancreatic intraepithelial neoplasia and pancreatic ductal adenocarcinoma
Susceptibility
  • not contributing to the susceptibility of bipolar affective disorder
  • to opioid dependence
  • Variant & Polymorphism other polymorphisms increasing the risk of opioid dependence
    Candidate gene useful indicator of the potential malignancy of epithelial cells of the pancreas
    Marker
    Therapy target
    ANIMAL & CELL MODELS