Other morbid association(s)
|
Type | Gene Modification | Chromosome rearrangement | Protein expression | Protein Function
|
---|
tumoral
|  
|  
| --low
|  
|
by hypoxia in tumor cells | tumoral
|  
| amplification
| --over
|  
|
in prostate carcinoma | tumoral
|  
|  
| --low
|  
|
in oral squamous cell carcinoma | tumoral
| somatic mutation
|  
|  
|  
|
in myelodysplastic syndromes, chronic myelogenous leukemia and acute myeloid leukemia | constitutional
| germinal mutation
|  
|  
|  
|
in chronic intestinal pseudo-obstruction, mutation that disrupt the ability of its product to regulate genes such as RUNX1 and APOB | |