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FLASH GENE
Symbol RAD21 contributors: mct - updated : 06-12-2017
HGNC name RAD21 homolog (S. pombe)
HGNC id 9811
ASSOCIATED DISORDERS
corresponding disease(s) CDLS4
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
tumoral     --low  
by hypoxia in tumor cells
tumoral   amplification --over  
in prostate carcinoma
tumoral     --low  
in oral squamous cell carcinoma
tumoral somatic mutation      
in myelodysplastic syndromes, chronic myelogenous leukemia and acute myeloid leukemia
constitutional germinal mutation      
in chronic intestinal pseudo-obstruction, mutation that disrupt the ability of its product to regulate genes such as RUNX1 and APOB
Susceptibility
Variant & Polymorphism
Candidate gene for CIPO3
Marker
Therapy target
ANIMAL & CELL MODELS