Symbol
| IMPDH1
| contributors: mct/pgu - updated : 14-03-2015
|
HGNC name
| IMP (inosine monophosphate) dehydrogenase 1
|
HGNC id
| 6052
|
Other morbid association(s)
|
Type | Gene Modification | Chromosome rearrangement | Protein expression | Protein Function
|
---|
tumoral
|  
|  
|  
|  
|
development of malignancy and the growth progression of some tumors | |
Susceptibility
|
to resistance to immunosuppressive drug, mycophenolic acid (MPA) |
Variant & Polymorphism
SNP
| increasing the risk of resistance to immunosuppressive drug, mycophenolic acid (MPA)( |
|
|
Candidate gene
| |
Marker
Therapy target
| | |
| 17-AAG is able to protect photoreceptor cells form degeneration in the RP10 mouse model by inducing heat shock proteins to reduce the formation of mutant Impdh1 aggregates ( | |
|