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FLASH GENE
Symbol PTPRD contributors: mct/npt/pgu - updated : 29-10-2016
HGNC name protein tyrosine phosphatase, receptor type, D
HGNC id 9668
ASSOCIATED DISORDERS
corresponding disease(s) RLLS3
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
tumoral   deletion    
in lung carcinoma, in neuroblastoma and cutaneous squamous cell carcinomas with metastases
tumoral   deletion --low  
expressed at lower levels in high stage neuroblastoma tumors, particularly those with amplification of MYCN, relative to low stage tumors or normal fetal adrenal neuroblasts
tumoral       loss of function
in glioblastoma multiforme (GBM), a deadly primary neoplasm of the brain
tumoral     --low  
in lung cancers
tumoral   deletion    
in metastatic cutaneous squamous cell carcinoma
Susceptibility
Variant & Polymorphism
Candidate gene
Marker
Therapy target
ANIMAL & CELL MODELS