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FLASH GENE
Symbol NQO2 contributors: mct - updated : 07-03-2008
HGNC name NAD(P)H dehydrogenase, quinone 2
HGNC id 7856
ASSOCIATED DISORDERS
corresponding disease(s)
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
tumoral     --over  
in ovarian carcinoma
Susceptibility to schizophrenia
Variant & Polymorphism insertion/deletion deletion of the 29 base pair sequence in the promoter may confer susceptibility to a certain form of schizophrenia
Candidate gene
Marker
Therapy target
  • therapeutic target in ovarian carcinoma, because the addition of the nonbiogenic electron donor dihydronicotinamide riboside (NRH) selectively potentiates the bioactivation of the alkylating agent tretazicar
  • potential target of the quinoline antimalarial compounds
  • ANIMAL & CELL MODELS