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FLASH GENE

Symbol

TAP1

contributors: mct - updated : 01-12-2016

HGNC name	transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
HGNC id	43

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

BLS1B

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function tumoral     --over   correlated with a more aggressive phenotype as well as worse prognosis in hepatocellular carcinoma patients

Susceptibility

to ankylosing spondytitis to alopecia areata (AA)

Variant & Polymorphism SNP	association between a promoter SNP (rs2071480) and susceptibility to AA

Candidate gene
Marker
Therapy target
	System Type Disorder Pubmed cancer digestive liver inhibition of TAP1 might provide new therapeutic approaches for HCC

ANIMAL & CELL MODELS