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FLASH GENE
Symbol TAP1 contributors: mct - updated : 01-12-2016
HGNC name transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
HGNC id 43
ASSOCIATED DISORDERS
corresponding disease(s) BLS1B
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
tumoral     --over  
correlated with a more aggressive phenotype as well as worse prognosis in hepatocellular carcinoma patients
Susceptibility
  • to ankylosing spondytitis
  • to alopecia areata (AA)
  • Variant & Polymorphism SNP
  • association between a promoter SNP (rs2071480) and susceptibility to AA
  • Candidate gene
    Marker
    Therapy target
    SystemTypeDisorderPubmed
    cancerdigestiveliver
    inhibition of TAP1 might provide new therapeutic approaches for HCC
    ANIMAL & CELL MODELS