Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol FABP3 contributors: mct - updated : 17-08-2011
HGNC name fatty acid binding protein 3, muscle and heart (mammary-derived growth inhibitor)
HGNC id 3557
ASSOCIATED DISORDERS
corresponding disease(s)
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
constitutional     --other  
aberrant expression may alter membrane fluidity and signal transduction, and consequently could be involved in cellular dysfunction in neurodegenerative disorders
Susceptibility to essential hypertension (EH)
Variant & Polymorphism SNP
  • G allele of rs2279885 and the C allele of rs2271072 were significantly higher in subjects with EH than in normotensive (NT) subjects
  • Candidate gene
    Marker
  • useful diagnostic marker for organ dysfunction, and its association with leptin will be a novel target for emergency aid
  • Therapy target
    SystemTypeDisorderPubmed
    obesity  
    potential target for modulation of energy dissipation
    ANIMAL & CELL MODELS
  • Fabp3(-/-) mice exhibit extreme cold sensitivity despite induction of uncoupling and oxidative genes and hydrolysis of brown adipose tissue lipid store