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FLASH GENE
Symbol F2R contributors: mct - updated : 18-01-2017
HGNC name coagulation factor II (thrombin) receptor
HGNC id 3537
ASSOCIATED DISORDERS
corresponding disease(s)
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
tumoral     --over  
in prostate cancer progression in androgen-dependent and -independent phases
tumoral     --over  
in blasts from acute myeloid leukemia, and in chronic myeloid leukemia patients in blast phase
Susceptibility
Variant & Polymorphism
Candidate gene
Marker
Therapy target
SystemTypeDisorderPubmed
immunologyinfectious 
therapeutics that target MMP1-F2R may prove beneficial in the treatment of sepsis
cancerdigestivestomach
potentially important therapeutic target for the treatment of gastric cancer.
ANIMAL & CELL MODELS