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FLASH GENE
Symbol RHOB contributors: mct/npt/pgu - updated : 18-09-2013
HGNC name ras homolog gene family, member B
HGNC id 668
ASSOCIATED DISORDERS
corresponding disease(s)
Susceptibility to osteoarthritis
Variant & Polymorphism SNP significant associations between 5' SNPs and osteoarthritis that hint at regulatory functions
Candidate gene
Marker
Therapy target
SystemTypeDisorderPubmed
cancerendocrinethyroid
target for therapeutic intervention in anaplastic thyroid cancer
neurology  
may represent an attractive target for therapeutic intervention in conditions involving elevated caspase 3 activity in the central nervous system
ANIMAL & CELL MODELS