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FLASH GENE
Symbol CSNK2A1 contributors: mct - updated : 26-02-2015
HGNC name casein kinase 2, alpha 1 polypeptide
HGNC id 2457
ASSOCIATED DISORDERS
corresponding disease(s)
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
tumoral     --over  
associated with hyperproliferation and suppression of apoptosis in cancer
constitutional       loss of function
resulted in an elevated level of insulin secretion
Susceptibility
Variant & Polymorphism
Candidate gene
Marker
Therapy target
SystemTypeDisorderPubmed
cancer  
selective CSNK2A1 inhibition or down-regulation in tumors may provide an attractive opportunity for the development of novel cancer therapies
cancer  
CSNK2A1 inhibitors, are potential therapies for multiple diseases that are driven by inflammation
ANIMAL & CELL MODELS