Symbol
| SRD5A2
| contributors: mct/npt - updated : 01-07-2008
|
HGNC name
| steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2)
|
HGNC id
| 11285
|
corresponding disease(s)
|
PPSH
|
Other morbid association(s)
|
Type | Gene Modification | Chromosome rearrangement | Protein expression | Protein Function
|
---|
tumoral
| somatic mutation
|  
|  
|  
|
in the prostate cancer in progression | |
Susceptibility
|
to prostate cancer to hypospadias or micropenis |
Variant & Polymorphism
SNP
, other
| mutation ala-49-thr increase the risk in african american men |
|
SNP V89L increases the risk of hypospadias |
|
|
Candidate gene
Marker
Therapy target
| | | |