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FLASH GENE
Symbol ADRA2B contributors: mct - updated : 24-03-2015
HGNC name adrenergic, alpha-2B-, receptor
HGNC id 282
ASSOCIATED DISORDERS
corresponding disease(s) BAFME2
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
constitutional   deletion    
deletion of region associated with reduced metabolism in obeses
Susceptibility
  • obesity
  • to idiopathic orthostatic intolerance (IOI)
  • Variant & Polymorphism other
  • beta1Gly49 polymorphism is protective for IOI
  • Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS