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FLASH GENE
Symbol WDR74 contributors: mct - updated : 09-11-2021
HGNC name WD repeat domain 74
HGNC id 25529
ASSOCIATED DISORDERS
corresponding disease(s)
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
tumoral     --over  
upon lung cancer progression from healthy normal tissues to the primary cancer and further to the metastatic cancer
Susceptibility
Variant & Polymorphism
Candidate gene
  • can serve as a candidate target for the prevention and treatment of lung cancer
  • Marker
    Therapy target
    ANIMAL & CELL MODELS
  • in Wdr74-deficient mouse embryos blocking Trp53 function rescues blastocyst formation and lineage differentiation