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FLASH GENE
Symbol LRIG3 contributors: mct - updated : 08-01-2020
HGNC name leucine rich repeats and immunoglobulin like domains 3
HGNC id 30991
ASSOCIATED DISORDERS
corresponding disease(s)
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
tumoral     --over  
might inhibit the viability, adhesion, invasion and migration and promote the apoptosis of Prostate cancer cells
Susceptibility
Variant & Polymorphism
Candidate gene
Marker
Therapy target
SystemTypeDisorderPubmed
cancerbrainglioma/neuroblstoma
restoration of LRIG3 may offer therapeutic potential against malignant gliomas
ANIMAL & CELL MODELS
  • Lrig3-deficient mice were smaller than the wild-type mice but otherwise appeared grossly normal