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FLASH GENE
Symbol KLLN contributors: mct - updated : 03-12-2015
HGNC name killin, p53-regulated DNA replication inhibitor
HGNC id 37212
ASSOCIATED DISORDERS
corresponding disease(s) CWS4
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
tumoral somatic mutation      
germline and somatic KLLN mutations in breast cancer dysregulate G2 arrest
Susceptibility
Variant & Polymorphism
Candidate gene
Marker
  • KLLN expression may be used in prostate carcinoma as a prognostic marker to predict outcome for intermediate risk patients, which could provide useful information for postoperative management
  • Therapy target
    SystemTypeDisorderPubmed
    cancerreproductivebreast
    might be used as a potential prognostic marker and novel therapy target for breast carcinomas
    ANIMAL & CELL MODELS