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FLASH GENE
Symbol GRK4 contributors: mct/npt - updated : 10-11-2014
HGNC name G protein-coupled receptor kinase 4
HGNC id 4543
ASSOCIATED DISORDERS
corresponding disease(s)
Susceptibility to essential hypertension
Variant & Polymorphism other
  • variant in isoform GRK4 gamma associated with essential hypertension
  • 65L allele is associated with stress-induced urinary sodium excretion reduction, suggesting impaired sodium handling in black normotensive adolescents
  • Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS