Symbol
| MTRNR2L1
| contributors: mct - updated : 29-12-2017
|
HGNC name
| MT-RNR2-like 1
|
HGNC id
| 37155
|
Other morbid association(s)
|
Type | Gene Modification | Chromosome rearrangement | Protein expression | Protein Function
|
---|
constitutional
|  
|  
| --low
|  
|
humanin signal is decreased in neurons of Alzheimer's disease patients | constitutional
|  
|  
| --low
|  
|
decline with age could play a role in the pathogenesis of age-related diseases including AD and T2 diabetes mellitus | constitutional
|  
|  
| --over
|  
|
in human IUGR-affected pregnancies on the maternal aspect of the placenta (extravillous trophoblastic (EVT) cytoplasm) compared to control | |
Variant & Polymorphism
|
| |
Candidate gene
Marker
Therapy target
|
System | Type | Disorder | Pubmed |
neurology | neurodegenerative | alzheimer | |
restoration or activation of the Humanin signal in neurons may change the course of AD | neurosensorial | visual | retina | |
potential role for MTRNR2L1 therapy in the prevention of retinal degeneration, including AMD |
| | | |