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FLASH GENE
Symbol MTRNR2L1 contributors: mct - updated : 29-12-2017
HGNC name MT-RNR2-like 1
HGNC id 37155
ASSOCIATED DISORDERS
corresponding disease(s)
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
constitutional     --low  
humanin signal is decreased in neurons of Alzheimer's disease patients
constitutional     --low  
decline with age could play a role in the pathogenesis of age-related diseases including AD and T2 diabetes mellitus
constitutional     --over  
in human IUGR-affected pregnancies on the maternal aspect of the placenta (extravillous trophoblastic (EVT) cytoplasm) compared to control
Susceptibility
Variant & Polymorphism
Candidate gene
Marker
Therapy target
SystemTypeDisorderPubmed
neurologyneurodegenerativealzheimer
restoration or activation of the Humanin signal in neurons may change the course of AD
neurosensorialvisualretina
potential role for MTRNR2L1 therapy in the prevention of retinal degeneration, including AMD
ANIMAL & CELL MODELS