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FLASH GENE
Symbol IDUA contributors: mct - updated : 14-11-2012
HGNC name iduronidase, alpha-L-
HGNC id 5391
ASSOCIATED DISORDERS
corresponding disease(s) MPS1
related resource Mucopolysaccharidosis
Susceptibility
Variant & Polymorphism
Candidate gene
Marker
Therapy target
ANIMAL & CELL MODELS
  • substantial elevation in heparan sulfate (HS) within the liver and brain of Idua -/- mice and significant changes in HS localization and sulfation patterning with significant increases in N-, 6-O-, and 2-O-sulfation