Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol GABRA2 contributors: mct - updated : 22-09-2020
HGNC name gamma-aminobutyric acid (GABA) A receptor, alpha 2
HGNC id 4076
ASSOCIATED DISORDERS
corresponding disease(s) EIEE78
Susceptibility
  • susceptibility to alcohol dependence by modulating the level of neural excitation
  • Variant & Polymorphism other genetic variations in GABRA2 might play a role in the risk of alcohol use disorders by moderating the subjective effects of alcohol
    Candidate gene
    Marker
    Therapy target
    SystemTypeDisorderPubmed
    psychiatry  
    may therefore represent a novel target for the development of more effective antidepressants
    ANIMAL & CELL MODELS
  • genetic inactivation of Gabra2 would generate a depressive-like phenotype in mice