Symbol
| SPRTN
| contributors: mct - updated : 20-06-2017
|
HGNC name
| SprT-like N-terminal domain
|
HGNC id
| 25356
|
corresponding disease(s)
|
RJALS
|
Other morbid association(s)
|
Type | Gene Modification | Chromosome rearrangement | Protein expression | Protein Function
|
---|
constitutional
|  
|  
| --low
|  
|
results in failure to repair DNA-protein crosslinks (DPCs) and hypersensitivity to DPC-inducing agents | |
Candidate gene
Marker
Therapy target
| | | |
| hypomorphic mice with low amounts of Spartan are viable, and are growth retarded and develop cataracts, lordokyphosis and cachexia at a young age |