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FLASH GENE
Symbol DEPDC1B contributors: mct/npt - updated : 21-04-2022
HGNC name DEP domain containing 1B
HGNC id 24902
ASSOCIATED DISORDERS
corresponding disease(s)
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
tumoral   LOH    
in BRCA1 breast tumors
tumoral     --over  
in prostate carcinoma, significantly associated with advanced clinical stage , advanced T stage and lymph node metastasis
Susceptibility
Variant & Polymorphism
Candidate gene
Marker
  • expression of DEPDC1B may be used as an independent predictor of biochemical recurrence-free survival time of patients with prostate carcinoma
  • Therapy target
    SystemTypeDisorderPubmed
    cancerdigestiveliver
    DEPDC1B was as a potential therapeutic target involved in HCC growth and progression
    ANIMAL & CELL MODELS